The route in which a drug is administered can influence the rate and degree to which the drug reaches its site of action<\/p>\n","media":{"disableImageZooming":false}},"library":"H5P.TrueFalse 1.6","metadata":{"contentType":"True\/False Question","license":"U","title":"Untitled True\/False Question"},"subContentId":"0a429f8f-d60a-407c-b636-0f141329180a"},{"params":{"text":"Fill in the missing words","overallFeedback":[{"from":0,"to":100}],"showSolutions":"Show solution","tryAgain":"Retry","checkAnswer":"Check","notFilledOut":"Please fill in all blanks to view solution","answerIsCorrect":"':ans' is correct","answerIsWrong":"':ans' is wrong","answeredCorrectly":"Answered correctly","answeredIncorrectly":"Answered incorrectly","solutionLabel":"Correct answer:","inputLabel":"Blank input @num of @total","inputHasTipLabel":"Tip available","tipLabel":"Tip","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"autoCheck":false,"caseSensitive":false,"showSolutionsRequiresInput":true,"separateLines":false,"confirmCheckDialog":false,"confirmRetryDialog":false,"acceptSpellingErrors":true},"scoreBarLabel":"You got :num out of :total points","confirmCheck":{"header":"Finish ?","body":"Are you sure you wish to finish ?","cancelLabel":"Cancel","confirmLabel":"Finish"},"confirmRetry":{"header":"Retry ?","body":"Are you sure you wish to retry ?","cancelLabel":"Cancel","confirmLabel":"Confirm"},"questions":["
Drug tolerance can be seen through the *dose-response curve*: a graph of the magnitude of effect of different doses of the drug to the right.<\/p>\n"],"media":{"disableImageZooming":false}},"library":"H5P.Blanks 1.12","metadata":{"contentType":"Fill in the Blanks","license":"U","title":"Untitled Fill in the Blanks"},"subContentId":"f1de822c-0362-496c-ac12-f7b1f1f4876a"},{"params":{"text":"Fill in the missing words","overallFeedback":[{"from":0,"to":100}],"showSolutions":"Show solution","tryAgain":"Retry","checkAnswer":"Check","notFilledOut":"Please fill in all blanks to view solution","answerIsCorrect":"':ans' is correct","answerIsWrong":"':ans' is wrong","answeredCorrectly":"Answered correctly","answeredIncorrectly":"Answered incorrectly","solutionLabel":"Correct answer:","inputLabel":"Blank input @num of @total","inputHasTipLabel":"Tip available","tipLabel":"Tip","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"autoCheck":false,"caseSensitive":false,"showSolutionsRequiresInput":true,"separateLines":false,"confirmCheckDialog":false,"confirmRetryDialog":false,"acceptSpellingErrors":true},"scoreBarLabel":"You got :num out of :total points","confirmCheck":{"header":"Finish ?","body":"Are you sure you wish to finish ?","cancelLabel":"Cancel","confirmLabel":"Finish"},"confirmRetry":{"header":"Retry ?","body":"Are you sure you wish to retry ?","cancelLabel":"Cancel","confirmLabel":"Confirm"},"questions":["
The two categories of changes that underlie drug tolerance are *metabolic* and functional<\/p>\n"],"media":{"disableImageZooming":false}},"library":"H5P.Blanks 1.12","metadata":{"contentType":"Fill in the Blanks","license":"U","title":"Untitled Fill in the Blanks"},"subContentId":"2edcd2a7-9927-43cf-adc8-7e83f52cf8f5"},{"params":{"text":"Fill in the missing words","overallFeedback":[{"from":0,"to":100}],"showSolutions":"Show solution","tryAgain":"Retry","checkAnswer":"Check","notFilledOut":"Please fill in all blanks to view solution","answerIsCorrect":"':ans' is correct","answerIsWrong":"':ans' is wrong","answeredCorrectly":"Answered correctly","answeredIncorrectly":"Answered incorrectly","solutionLabel":"Correct answer:","inputLabel":"Blank input @num of @total","inputHasTipLabel":"Tip available","tipLabel":"Tip","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"autoCheck":false,"caseSensitive":false,"showSolutionsRequiresInput":true,"separateLines":false,"confirmCheckDialog":false,"confirmRetryDialog":false,"acceptSpellingErrors":true},"scoreBarLabel":"You got :num out of :total points","confirmCheck":{"header":"Finish ?","body":"Are you sure you wish to finish ?","cancelLabel":"Cancel","confirmLabel":"Finish"},"confirmRetry":{"header":"Retry ?","body":"Are you sure you wish to retry ?","cancelLabel":"Cancel","confirmLabel":"Confirm"},"questions":["
The role of Learning in Drug Tolerance has focused on two phenomena: 1.*Contingent drug tolerance*: tolerance develops only to drug effects that are actually experienced. and 2. *Conditioned drug tolerance*: tolerance effects are maximally expressed only when a drug is administered in same situation it has previously been administered.<\/p>\n"],"media":{"disableImageZooming":false}},"library":"H5P.Blanks 1.12","metadata":{"contentType":"Fill in the Blanks","license":"U","title":"Untitled Fill in the Blanks"},"subContentId":"957bd978-d0c4-46fc-af2b-43741beeb38c"},{"params":{"taskDescription":"Drag the words into the correct boxes","overallFeedback":[{"from":0,"to":100}],"checkAnswer":"Check","tryAgain":"Retry","showSolution":"Show solution","dropZoneIndex":"Drop Zone @index.","empty":"Drop Zone @index is empty.","contains":"Drop Zone @index contains draggable @draggable.","ariaDraggableIndex":"@index of @count draggables.","tipLabel":"Show tip","correctText":"Correct!","incorrectText":"Incorrect!","resetDropTitle":"Reset drop","resetDropDescription":"Are you sure you want to reset this drop zone?","grabbed":"Draggable is grabbed.","cancelledDragging":"Cancelled dragging.","correctAnswer":"Correct answer:","feedbackHeader":"Feedback","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"instantFeedback":false},"scoreBarLabel":"You got :num out of :total points","textField":"*Smoker\u2019s syndrome* involves chest pain, labored breathing, wheezing, coughing, and susceptibility to respiratory infections. People can also become susceptible to lethal lung disorders, such as pneumonia, *bronchitis*, emphysema, lung cancer, cancer of larynx, mouth, kidneys, bladder, pancreas & stomach. They are also at increased risk of *cardiovascular disorders*, which can culminate in a heart attack or stroke. Long-term smoking can also lead to *Buerger\u2019s disease* where blood vessels become constricted, especially those supplying blood to legs and in some cases toes, foot, ankle, leg, need to be amputated."},"library":"H5P.DragText 1.8","metadata":{"contentType":"Drag Text","license":"U","title":"Untitled Drag Text"},"subContentId":"fe65f55b-35fc-4fb7-8f6a-0e6bd8ad5809"},{"params":{"correct":"true","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"confirmCheckDialog":false,"confirmRetryDialog":false,"autoCheck":false},"l10n":{"trueText":"True","falseText":"False","score":"You got @score of @total points","checkAnswer":"Check","showSolutionButton":"Show solution","tryAgain":"Retry","wrongAnswerMessage":"Wrong answer","correctAnswerMessage":"Correct answer","scoreBarLabel":"You got :num out of :total points"},"confirmCheck":{"header":"Finish ?","body":"Are you sure you wish to finish ?","cancelLabel":"Cancel","confirmLabel":"Finish"},"confirmRetry":{"header":"Retry ?","body":"Are you sure you wish to retry ?","cancelLabel":"Cancel","confirmLabel":"Confirm"},"question":"
The effects of Chronic Alcohol Consumption can lead to Korsakoff\u2019s syndrome, which involves brain damage, memory loss, and sensory and motor dysfunction.<\/p>\n","media":{"disableImageZooming":false}},"library":"H5P.TrueFalse 1.6","metadata":{"contentType":"True\/False Question","license":"U","title":"Untitled True\/False Question"},"subContentId":"ab9c746c-90be-4bf5-8646-14d57f97f159"},{"params":{"text":"Fill in the missing words","overallFeedback":[{"from":0,"to":100}],"showSolutions":"Show solution","tryAgain":"Retry","checkAnswer":"Check","notFilledOut":"Please fill in all blanks to view solution","answerIsCorrect":"':ans' is correct","answerIsWrong":"':ans' is wrong","answeredCorrectly":"Answered correctly","answeredIncorrectly":"Answered incorrectly","solutionLabel":"Correct answer:","inputLabel":"Blank input @num of @total","inputHasTipLabel":"Tip available","tipLabel":"Tip","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"autoCheck":false,"caseSensitive":false,"showSolutionsRequiresInput":true,"separateLines":false,"confirmCheckDialog":false,"confirmRetryDialog":false,"acceptSpellingErrors":true},"scoreBarLabel":"You got :num out of :total points","confirmCheck":{"header":"Finish ?","body":"Are you sure you wish to finish ?","cancelLabel":"Cancel","confirmLabel":"Finish"},"confirmRetry":{"header":"Retry ?","body":"Are you sure you wish to retry ?","cancelLabel":"Cancel","confirmLabel":"Confirm"},"questions":["
The main forms of medicated drug treatment for heroin addiction include *Methadone* and Buprenorphine<\/p>\n"],"media":{"disableImageZooming":false}},"library":"H5P.Blanks 1.12","metadata":{"contentType":"Fill in the Blanks","license":"U","title":"Untitled Fill in the Blanks"},"subContentId":"06e927b4-c169-4ca3-8c9c-b95e9b04e581"},{"params":{"text":"Fill in the missing words","overallFeedback":[{"from":0,"to":100}],"showSolutions":"Show solution","tryAgain":"Retry","checkAnswer":"Check","notFilledOut":"Please fill in all blanks to view solution","answerIsCorrect":"':ans' is correct","answerIsWrong":"':ans' is wrong","answeredCorrectly":"Answered correctly","answeredIncorrectly":"Answered incorrectly","solutionLabel":"Correct answer:","inputLabel":"Blank input @num of @total","inputHasTipLabel":"Tip available","tipLabel":"Tip","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"autoCheck":false,"caseSensitive":false,"showSolutionsRequiresInput":true,"separateLines":false,"confirmCheckDialog":false,"confirmRetryDialog":false,"acceptSpellingErrors":true},"scoreBarLabel":"You got :num out of :total points","confirmCheck":{"header":"Finish ?","body":"Are you sure you wish to finish ?","cancelLabel":"Cancel","confirmLabel":"Finish"},"confirmRetry":{"header":"Retry ?","body":"Are you sure you wish to retry ?","cancelLabel":"Cancel","confirmLabel":"Confirm"},"questions":["
In the brain there is circuitry that reinforces behaviour and species (inc. humans) will administer brief bursts of weak electrical stimulation to them. This is known as *intracranial self-stimulation* <\/p>\n"],"media":{"disableImageZooming":false}},"library":"H5P.Blanks 1.12","metadata":{"contentType":"Fill in the Blanks","license":"U","title":"Untitled Fill in the Blanks"},"subContentId":"aeb11a18-654a-4586-881e-597ee8cc71ae"},{"params":{"taskDescription":"Drag the words into the correct boxes","overallFeedback":[{"from":0,"to":100}],"checkAnswer":"Check","tryAgain":"Retry","showSolution":"Show solution","dropZoneIndex":"Drop Zone @index.","empty":"Drop Zone @index is empty.","contains":"Drop Zone @index contains draggable @draggable.","ariaDraggableIndex":"@index of @count draggables.","tipLabel":"Show tip","correctText":"Correct!","incorrectText":"Incorrect!","resetDropTitle":"Reset drop","resetDropDescription":"Are you sure you want to reset this drop zone?","grabbed":"Draggable is grabbed.","cancelledDragging":"Cancelled dragging.","correctAnswer":"Correct answer:","feedbackHeader":"Feedback","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"instantFeedback":false},"scoreBarLabel":"You got :num out of :total points","textField":"Initial drug taking is\u00a0mediated in same way as pleasure activity, with the *mesocorticolimbic* pathway and\u00a0particularly the *nucleus accumbens* playing a key role. But it does not act alone. Instead it interacts with three other areas: *Prefrontal lobes*: role in decision making; *Hippocampus*: provides info about previous experiences; and *Amygdala*: coordinates positive and negative reactions."},"library":"H5P.DragText 1.8","metadata":{"contentType":"Drag Text","license":"U","title":"Untitled Drag Text"},"subContentId":"0f8b09c7-f2ca-424e-bca3-3b18ba2ec0eb"},{"params":{"text":"Fill in the missing words","overallFeedback":[{"from":0,"to":100}],"showSolutions":"Show solution","tryAgain":"Retry","checkAnswer":"Check","notFilledOut":"Please fill in all blanks to view solution","answerIsCorrect":"':ans' is correct","answerIsWrong":"':ans' is wrong","answeredCorrectly":"Answered correctly","answeredIncorrectly":"Answered incorrectly","solutionLabel":"Correct answer:","inputLabel":"Blank input @num of @total","inputHasTipLabel":"Tip available","tipLabel":"Tip","behaviour":{"enableRetry":true,"enableSolutionsButton":true,"enableCheckButton":true,"autoCheck":false,"caseSensitive":false,"showSolutionsRequiresInput":true,"separateLines":false,"confirmCheckDialog":false,"confirmRetryDialog":false,"acceptSpellingErrors":true},"scoreBarLabel":"You got :num out of :total points","confirmCheck":{"header":"Finish ?","body":"Are you sure you wish to finish ?","cancelLabel":"Cancel","confirmLabel":"Finish"},"confirmRetry":{"header":"Retry ?","body":"Are you sure you wish to retry ?","cancelLabel":"Cancel","confirmLabel":"Confirm"},"questions":["
Drug Relapse is thought to be triggered by 3 factors: Stress, *priming* and environmental cues<\/p>\n"],"media":{"disableImageZooming":false}},"library":"H5P.Blanks 1.12","metadata":{"contentType":"Fill in the Blanks","license":"U","title":"Untitled Fill in the Blanks"},"subContentId":"5e45605f-f081-46d2-b583-c2467ff050a9"}],"disableBackwardsNavigation":false,"randomQuestions":false,"endGame":{"showResultPage":true,"showSolutionButton":true,"noResultMessage":"Finished","message":"Your result:","overallFeedback":[{"from":0,"to":100}],"solutionButtonText":"Show solution","retryButtonText":"Retry","finishButtonText":"Finish","showAnimations":false,"skippable":false,"skipButtonText":"Skip video","showRetryButton":true},"override":{"checkButton":true},"texts":{"prevButton":"Previous question","nextButton":"Next question","finishButton":"Finish","textualProgress":"Question: @current of @total questions","jumpToQuestion":"Question %d of %total","questionLabel":"Question","readSpeakerProgress":"Question @current of @total","unansweredText":"Unanswered","answeredText":"Answered","currentQuestionText":"Current question"},"backgroundImage":{"path":"images\/backgroundImage-5e7377c047df7.jpg","mime":"image\/jpeg","copyright":{"license":"U"},"width":251,"height":201}}